Examining the effect of a mindfulness based program for the improvement of cognitive function in an early stage of schizophrenia. A random controlled trial

ABSTRACT

Mindfulness based interventions (MBIs) are standardized group programs used in clinical and health contexts. In psychosis three meta-analyses that considered only RCTs suggested that MBIs have an effect on psychotic symptoms as primary outcome, with a greater effect on negative rather than positive symptoms (Khoury et al., 2013; Jansen et al., 2020; Louise et al., 2018). However, their effect on a fundamental element of schizophrenia such as Cognitive Impairments (CI) has not been explored. CI has been described as a core element that evolves during and after the course of the illness (Kelleher et al., 2013). Several authors have found that people after a first psychotic episode exhibit worsened cognitive functioning compared to control groups (e.g. Aas et al., 2014). MBIs have shown promising effects on cognitive functions in the general population, such as improvements in working memory and attention (for a review, see Raffone and Srinivasan, 2017) and even in social cognition in outpatients with chronic schizophrenia (Mediavilla et al., 2019). In this study, we propose to test the effect of eight sessions of adapted MBIs for psychosis in patients with early onset schizophrenia. Specifically, we measured cognitive functions as primary outcome

Álvaro I Langer, Carlos Schmidt, Rodrigo Vergara, Rocío Mayol-Troncoso, Javiera Lecaros, Edwin Krogh, Carolina Vergara, Marcela Díaz, Gerardo Rivera, Rodrigo Aguirre-Baez, Pablo A Gaspar

Schizophrenia Research

agosto 03, 2020

DOI: 10.1016/j.schres.2020.07.012.

Investigador BNI: Pablo Gaspar